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Scientists at the University of Georgia have developed a vaccine to protect against dangerous fungi.
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The vaccine has been tested on mice and rhesus macaques, and was effective in preventing infections and deaths caused by three common fungi.
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The vaccine trains the immune system to recognize a "pan-fungal" protein shared by these fungi, boosting immunity.
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The vaccine is aimed at immunocompromised people, who are at a higher risk of fatal fungal infections.
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Fungal infections are expected to rise as more people live with conditions that weaken their immune system.
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There are very few safe antifungal drugs and no approved vaccines against fungal infections.
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The vaccine has the potential to be groundbreaking in preventing invasive fungal infections.
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13 million life-threatening fungal infections occur annually worldwide, with these three fungi accounting for over 80% of fungal-related deaths.
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Fungal infections result in an estimated $6.7 billion in direct medical costs annually in the U.S. alone.
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The team is preparing for a Phase I trial to assess the vaccine's safety and immune response in healthy human volunteers.