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The first-ever vaccine in the world for honeybees was approved to be used by the US government.
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The hope of a novel weapon to fight diseases that regularly ruin colonies relied on to pollinate food.
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The US Department of Agriculture (USDA) has issued an interim license to an experimental vaccine.
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It was created by Dalan Animal Health to help honeybees be protected from American foulbrood.
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"Our vaccine is a breakthrough in protecting honeybees," said Annette Kleiser, chief executive of Dalan Animal Health.
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"We are ready to change how we care for insects, impacting food production on a global scale."
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The vaccine will be initially accessible to commercial beekeepers.
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It is designed to reduce foulbrood, which is a deadly illness that is caused by the bacteria called Paenibacillus larvae which weakens and kills hives.
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There is no cure currently for the illness.
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An entomologist from The University of Georgia has collaborated with Dalan to develop the vaccine.